Interferon Lambda Protects Gastrointestinal Stem Cells from Acute Gvhd
نویسندگان
چکیده
منابع مشابه
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD.
CD4+CD25+ regulatory T (Treg) cells are potent modulators of alloimmune responses. In murine models of allogeneic bone marrow transplantation, adoptive transfer of donor CD4+CD25+ Treg cells protects recipient mice from lethal acute graft-versus-host disease (aGVHD) induced by donor CD4+CD25- T cells. Here we examined the differential effect of CD62L+ and CD62L- subsets of CD4+CD25+ Treg cells ...
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ژورنال
عنوان ژورنال: Transplantation and Cellular Therapy
سال: 2021
ISSN: 2666-6367
DOI: 10.1016/s2666-6367(21)00107-x